593-31-7

593-31-7 structure

Name: (Z)-3-(9-octadecenyloxy)propane-1,2-diol
Chemical Name: 3-[(E)-octadec-9-enoxy]propane-1,2-diol
CAS Number: 593-31-7
Molecular Formula: C₂₁H₄₂O₃
Molecular Weight: 342.55600
Catalog: Research Areas Cardiovascular Disease
Create Date: 2017-02-18 23:51:40
Modify Date: 2024-01-05 22:30:18
Selachyl alcohol is an orally active antihypertensive agent. Selachyl alcohol has similar activities with antihypertensive neutral renomedullary lipid (ANRL). Selachyl alcohol is an alkylglycerol compound in shark liver oil mixture with properties that reduce lung metastasis. Selachyl alcohol can be used for cardiovascular disease research[1][2].

Name	3-[(E)-octadec-9-enoxy]propane-1,2-diol
Synonyms	Glyceryl monooleyl ether 1-oleylglycerol 3-octadec-9c-enyloxy-propane-1,2-diol 1-glyceryl monoleyl ether EINECS 209-787-7 selachyl alcohol 1-O-cis-9-octadecenylglycerol Octadec-9-enylglycerol

Description	Selachyl alcohol is an orally active antihypertensive agent. Selachyl alcohol has similar activities with antihypertensive neutral renomedullary lipid (ANRL). Selachyl alcohol is an alkylglycerol compound in shark liver oil mixture with properties that reduce lung metastasis. Selachyl alcohol can be used for cardiovascular disease research[1][2].
Related Catalog	Research Areas >> Cardiovascular Disease
In Vivo	Selachyl alcohol (5 和 10 mg，灌胃，5 次；1 mg，静脉注射，1 次) 降低高血压小鼠的血压[1]。 Animal Model: Male Sprague-Dawley rats with hypertension[1] Dosage: 5 and 10 mg (oral gavage); 1 mg (i.v.) Administration: Oral gavage, 5 and 10 mg, 10 occasions; intravenous injection, 1 mg, once Result: Induced blood pressure drops slowly about 60 mm Hg and remains for 20 minutes. Effectively reduced blood pressure by gastrointestinal tract.
References	[1]. Muirhead EE, et al. Selachyl alcohol as an oral antihypertensive agent: a preliminary note. Am J Med Sci. 1987 Nov;294(5):384-7. [2]. Momha R, et al. Anti-Angiogenic and Cytotoxicity Effects of Selachyl Alcohol Analogues. Anticancer Agents Med Chem. 2022;22(10):1913-1920.