94161-07-6

94161-07-6 structure

Name: N-(DITHIOCARBAMOYL)-N-METHYL-D-GLUCAMINE, SODIUM SALT
Chemical Name: methyl-[(2S,3R,4R,5R)-2,3,4,5,6-pentahydroxyhexyl]carbamodithioic acid
CAS Number: 94161-07-6
Molecular Formula: C₈H₁₇N₂NaO₅S₂
Molecular Weight: 308.35100
Catalog: Research Areas Inflammation/Immunology
Create Date: 2016-02-28 10:49:36
Modify Date: 2024-01-03 14:03:23
N-methyl-N-dithiocarboxyglucamine (MDCG) mobilizes and promotes excretion of metallothione-bound 109Cd. N-methyl-N-dithiocarboxyglucamine shows effects on acute and chronic Cd intoxication[1].

Name	methyl-[(2S,3R,4R,5R)-2,3,4,5,6-pentahydroxyhexyl]carbamodithioic acid
Synonyms	N-Methyl-D-glucamine dithiocarbamate

Description	N-methyl-N-dithiocarboxyglucamine (MDCG) mobilizes and promotes excretion of metallothione-bound 109Cd. N-methyl-N-dithiocarboxyglucamine shows effects on acute and chronic Cd intoxication[1].
Related Catalog	Research Areas >> Inflammation/Immunology
In Vivo	N-methyl-N-dithiocarboxyglucamine (684-2736 mg/kg；腹腔注射，每日注射 3 次) 3 天内有效促进粪便镉排泄[1]。 N-methyl-N-dithiocarboxyglucamine (2736 mg/kg；腹腔注射，每周注射 3 次) 降低肾脏和肝脏的镉水平[1]。 Animal Model: Mice with CdCl2 injection[1] Dosage: 684, 1368 and 2736 mg/kg Administration: Intraperitoneal injection; 684, 1368 and 2736 mg/kg, three daily injection Result: Dose-dependently increased fecal Cd excretion and caused a fecal Cd excretion of almost 30% of the administered Cd over a 3-day period at a dose of 2736 mg/kg.
References	[1]. Gale GR, et al. Effects of sodium N-methyl-N-dithiocarboxyglucamine on cadmium distribution and excretion. Life Sci. 1984 Dec 17;35(25):2571-8.