Name | (S)-N-(2-(2-(methylsulfonyl)-1-(3-(ethoxy-d5)-4-(methoxy)phenyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide |
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Synonyms |
Apremilast D5
Apremilast-d5 |
Description | Apremilast D5 (CC-10004 D5) is a deuterium labeled Apremilast. Apremilast is an orally available inhibitor of type-4 cyclic nucleotide phosphodiesterase (PDE-4) with an IC50 of 74 nM. Apremilast inhibits TNF-α release by lipopolysaccharide (LPS) with an IC50 of 104 nM[1]. |
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Related Catalog | |
Target |
PDE4 TNF-α |
References |
Molecular Formula | C22H19D5N2O7S |
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Molecular Weight | 465.53100 |
Exact Mass | 465.16200 |
PSA | 127.46000 |
LogP | 3.52590 |