120128-14-5

120128-14-5 structure

Name: thrazarine
Chemical Name: (Z,3R)-1-[(2S)-2-amino-2-carboxyethoxy]-2-diazonio-3-hydroxybut-1-en-1-olate
CAS Number: 120128-14-5
Molecular Formula: C₇H₁₁N₃O₅
Molecular Weight: 217.17900
Catalog: Research Areas Cancer
Create Date: 2017-07-18 21:20:40
Modify Date: 2025-09-11 09:24:00
Thrazarine (FR 900840) is an oncology antibiotic that can be produced by Streptomyces coerulescens MH802-fF5. Thrazarine directly inhibits DNA synthesis and tumor cell growth. Thrazarine can specifically induce lysis of tumor cells co-cultured with non-activated macrophages. Thrazarine is used in cancer research[1].

Name	(Z,3R)-1-[(2S)-2-amino-2-carboxyethoxy]-2-diazonio-3-hydroxybut-1-en-1-olate
Synonyms	Thrazarine

Description	Thrazarine (FR 900840) is an oncology antibiotic that can be produced by Streptomyces coerulescens MH802-fF5. Thrazarine directly inhibits DNA synthesis and tumor cell growth. Thrazarine can specifically induce lysis of tumor cells co-cultured with non-activated macrophages. Thrazarine is used in cancer research[1].
Related Catalog	Research Areas >> Cancer
References	[1]. Kameyama T, et al. Thrazarine, a new antitumor antibiotic. I. Taxonomy, fermentation, isolation and biological properties. J Antibiot (Tokyo). 1988 Nov;41(11):1561-7.