93909-48-9

93909-48-9 structure
93909-48-9 structure
  • Name: Propafenone-(phenyl-d5) (hydrochloride)
  • Chemical Name: 1-Propanone, 1-[2-[2-hydroxy-3-(propylamino)propoxy]phenyl]-3-(phenyl-d5)-, hydrochloride
  • CAS Number: 93909-48-9
  • Molecular Formula: C21H28ClNO3
  • Molecular Weight: 377.90500
  • Catalog: Signaling Pathways Membrane Transporter/Ion Channel Sodium Channel
  • Create Date: 2016-04-14 04:40:42
  • Modify Date: 2024-01-06 16:46:02
  • Propafenone-(phenyl-dd5) (hydrochloride) is the deuterium labeled Propafenone hydrochloride[1]. Propafenone hydrochloride is a class of anti-arrhythmic medication, which treats illnesses associated with rapid heart beats such as atrial and ventricular arrhythmias[2].

Name 1-Propanone, 1-[2-[2-hydroxy-3-(propylamino)propoxy]phenyl]-3-(phenyl-d5)-, hydrochloride
Synonyms PROPAFENONE D5
Propafenone D5 Hydrochloride
Description Propafenone-(phenyl-dd5) (hydrochloride) is the deuterium labeled Propafenone hydrochloride[1]. Propafenone hydrochloride is a class of anti-arrhythmic medication, which treats illnesses associated with rapid heart beats such as atrial and ventricular arrhythmias[2].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. http://en.wikipedia.org/wiki/Propafenone

Molecular Formula C21H28ClNO3
Molecular Weight 377.90500
Exact Mass 377.17600
PSA 58.56000
LogP 4.43430