1036959-27-9
1036959-27-9 structure
- Name: (2R)-1-[2-[(3-Hydroxytricyclo[3.3.1.1(3,7)]dec-1-yl)amino]acetyl]-2-pyrrolidinecarbonitrile
- Chemical Name: vildagliptin
- CAS Number: 1036959-27-9
- Molecular Formula: C17H25N3O2
- Molecular Weight: 303.40
- Catalog: Research Areas Metabolic Disease
- Create Date: 2018-06-15 15:25:56
- Modify Date: 2024-01-07 17:20:32
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(2R)-Vildagliptin is the inactive isomer of Vildagliptin (HY-14291), and can be used as an experimental control. Vildagliptin (LAF237) is a potent, stable, selective dipeptidyl peptidase IV (DPP-IV) inhibitor with an IC50 of 3.5 nM in human Caco-2 cells. Vildagliptin possesses excellent oral bioavailability and potent antihyperglycemic activity[1].
| Name | vildagliptin |
|---|---|
| Synonyms |
(R)-1-[2-((5S,7S)-3-hydroxy-adamantan-1-ylamino)-acetyl]-pyrrolidine-2-carbonitrile
2-Pyrrolidinecarbonitrile, 1-[2-[(3-hydroxytricyclo[3.3.1.1]dec-1-yl)amino]acetyl]-, (2R)- (2R)-Vildagliptin (2R)-1-[N-(3-Hydroxyadamantan-1-yl)glycyl]-2-pyrrolidinecarbonitrile |
| Description | (2R)-Vildagliptin is the inactive isomer of Vildagliptin (HY-14291), and can be used as an experimental control. Vildagliptin (LAF237) is a potent, stable, selective dipeptidyl peptidase IV (DPP-IV) inhibitor with an IC50 of 3.5 nM in human Caco-2 cells. Vildagliptin possesses excellent oral bioavailability and potent antihyperglycemic activity[1]. |
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| Related Catalog | |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 531.3±50.0 °C at 760 mmHg |
| Molecular Formula | C17H25N3O2 |
| Molecular Weight | 303.40 |
| Flash Point | 275.1±30.1 °C |
| Exact Mass | 303.194672 |
| PSA | 76.36000 |
| LogP | -0.14 |
| Vapour Pressure | 0.0±3.2 mmHg at 25°C |
| Index of Refraction | 1.601 |