867257-26-9

867257-26-9 structure
867257-26-9 structure
  • Name: Tecarfarin
  • Chemical Name: (1,1,1,3,3,3-hexafluoro-2-methylpropan-2-yl) 4-[(4-hydroxy-2-oxochromen-3-yl)methyl]benzoate
  • CAS Number: 867257-26-9
  • Molecular Formula: C21H14F6O5
  • Molecular Weight: 460.32300
  • Catalog: Signaling Pathways Others Others
  • Create Date: 2018-12-13 07:31:36
  • Modify Date: 2025-08-25 10:56:24
  • Tecarfarin (ATI-5923) is an orally active and non-competitive vitamin K epoxide reductase (VKOR) antagonist, and impairs the activation of the vitamin K-dependent clotting factors II, VII, IX and X[1]. Tecarfarin has the antithrombotic activity [2].

Name (1,1,1,3,3,3-hexafluoro-2-methylpropan-2-yl) 4-[(4-hydroxy-2-oxochromen-3-yl)methyl]benzoate
Synonyms tecarfarin
ati-5923
unii-wn1479yt50
Description Tecarfarin (ATI-5923) is an orally active and non-competitive vitamin K epoxide reductase (VKOR) antagonist, and impairs the activation of the vitamin K-dependent clotting factors II, VII, IX and X[1]. Tecarfarin has the antithrombotic activity [2].
Related Catalog
Target

VKOR[1]

References

[1]. Hobl EL, et al. Tecarfarin: A Novel Vitamin K Antagonist. Thromb Haemost. 2017 Nov;117(11):2009-2011.

[2]. Bowersox SS, et al. Antithrombotic activity of the novel oral anticoagulant, Tecarfarin [Sodium 3-[4-((1,1,1,3,3,3-hexafluoro-2-methylpropan-2-yloxy) carbonyl) benzyl]-2-oxo-2H-chromen-4-olate] in animal models. Thromb Res. 2010 Nov;126(5):e383-8.

Molecular Formula C21H14F6O5
Molecular Weight 460.32300
Exact Mass 460.07500
PSA 76.74000
LogP 5.12950
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