1092578-46-5
1092578-46-5 structure
- Name: (3R,4S)-Tofacitinib
- Chemical Name: 3-[(3R,4S)-4-methyl-3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl]-3-oxopropanenitrile
- CAS Number: 1092578-46-5
- Molecular Formula: C16H20N6O
- Molecular Weight: 312.370
- Catalog: Research Areas Inflammation/Immunology
- Create Date: 2018-12-26 17:44:53
- Modify Date: 2025-08-25 10:02:53
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(3R,4S)-Tofacitinib is an enantiomer of Tofacitinib. Tofacitinib inhibits JAK3 with IC50 of 1 nM.
| Name | 3-[(3R,4S)-4-methyl-3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl]-3-oxopropanenitrile |
|---|---|
| Synonyms |
(3R,4S)-Tofacitinib|
CS-1109 1-Piperidinepropanenitrile,4-methyl-3-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)--oxo-,(3R,4S) 3-((3R,4S)-4-Methyl-3-(Methyl(7H-pyrrolo[2,3-d]pyriMidin-4-yl)aMino)piperidin-1-yl)-3-oxopropanenitrile 3-((3R,4S)-3-((1H-Indol-4-yl)(methyl)amino)-4-methylpiperidin-1-yl)-3-oxopropan-enitrile (3R,4S)-Tofacitinib |
| Description | (3R,4S)-Tofacitinib is an enantiomer of Tofacitinib. Tofacitinib inhibits JAK3 with IC50 of 1 nM. |
|---|---|
| Related Catalog |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 585.8±50.0 °C at 760 mmHg |
| Molecular Formula | C16H20N6O |
| Molecular Weight | 312.370 |
| Flash Point | 308.1±30.1 °C |
| Exact Mass | 312.169861 |
| PSA | 88.91000 |
| LogP | 0.93 |
| Vapour Pressure | 0.0±1.6 mmHg at 25°C |
| Index of Refraction | 1.646 |
| Storage condition | -20°C |