955272-06-7
955272-06-7 structure
- Name: GKT136901
- Chemical Name: 2-(2-Chlorophenyl)-4-methyl-5-(pyridin-2-ylmethyl)-1H-pyrazolo[4,3-c]pyridine-3,6(2H,5H)-dione
- CAS Number: 955272-06-7
- Molecular Formula: C19H15ClN4O2
- Molecular Weight: 366.80100
- Create Date: 2016-11-27 01:05:03
- Modify Date: 2024-02-02 13:35:48
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GKT136901 is a potent, selective and orally active inhibitor of NADPH oxidase (NOX1/4), with Kis of 160 and 165 nM, respectively. GKT136901 also is a selective and direct scavenger of peroxynitrite. GKT136901 can be used for the research of diabetic nephropathy, stroke, and neurodegeneration. GKT136901 also has anti-inflammatory activity.
| Name | 2-(2-Chlorophenyl)-4-methyl-5-(pyridin-2-ylmethyl)-1H-pyrazolo[4,3-c]pyridine-3,6(2H,5H)-dione |
|---|---|
| Synonyms | 2-(2-chlorophenyl)-4-methyl-5-(pyridin-2-ylmethyl)-1H-pyrazolo[4,3-c]pyridine-3,6-dione |
| Molecular Formula | C19H15ClN4O2 |
|---|---|
| Molecular Weight | 366.80100 |
| Exact Mass | 366.08800 |
| PSA | 72.68000 |
| LogP | 2.88560 |
| HS Code | 2933990090 |
|---|
| HS Code | 2933990090 |
|---|---|
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |