T2 toxin Triol

Names

[ Name ]:
T2 toxin Triol

[Synonym ]:
T 2 triol
Deacetyl HT 2 toxin
Toxin T 2 triol
Spiro[2,5-methano-1-benzoxepin-10,2'-oxirane], trichothec-9-ene-3,4,8,15-tetrol deriv.
Trichothec-9-ene-3α,4β,8α,15-tetrol, 12,13-epoxy-, 8-isovalerate

Biological Activity

[Description]:

T2 toxin Triol is a trichothecene mycotoxin derived by the metabolism of T-2 toxin. It is less toxic than T-2 toxin[1]. T2 toxin Triol major metabolites are evaluated in broiler chickens with Half-lives (t1/2λz), Peak plasma concentrations (Cmax) and Tmax values of 9.6 mins, 563 ng/ml , 2.5 mins, respectively[2].

[Related Catalog]:

Research Areas >> Metabolic Disease

[References]

[1]. Li Y, et al. T-2 toxin, a trichothecene mycotoxin: review of toxicity, metabolism, and analytical methods. J Agric Food Chem. 2011 Apr 27;59(8):3441-53.

[2]. Sun YX, et al. Toxicokinetics of T-2 toxin and its major metabolites in broiler chickens after intravenous and oral administration. J Vet Pharmacol Ther. 2015 Feb;38(1):80-5.

Chemical & Physical Properties

[ Density]:
1.32±0.1 g/cm3(20 °C , 760mmHg)

[ Boiling Point ]:
527.1±50.0 °C (760 mmHg)

[ Molecular Formula ]:
C₂₀H₃₀O₇

[ Molecular Weight ]:
382.44800

[ Exact Mass ]:
382.19900

[ PSA ]:
108.75000

[ LogP ]:
0.55110

Related Compounds

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