3′,5-Dihydroxy-4′,6,7-trimethoxyflavanone

Names

[ Name ]:
3′,5-Dihydroxy-4′,6,7-trimethoxyflavanone

[Synonym ]:
(2S)-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-6,7-dimethoxy-2,3-dihydrochromen-4-one

Biological Activity

[Description]:

3′,5-Dihydroxy-4′,6,7-trimethoxyflavanone is a nature product that could be isolated from the fruits of Vitex rotundifolia. 3′,5-Dihydroxy-4′,6,7-trimethoxyflavanone has potent cytotoxic activity against A549 and HepG-2 cell lines[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[In Vitro]

3',5-Dihydroxy-4',6,7-trimethoxyflavanone (compound 10; 36 h) 具有细胞毒活性，对 HepG-2 和 A549 细胞的 IC50 值分别为 35 和 >100 μM[1]。

[References]

[1]. Zhao YY, et, al. A new iridoid glycoside from the fruits of Vitex rotundifolia. Nat Prod Res. 2017 Nov;31(21):2491-2496.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₈H₁₈O₇

[ Molecular Weight ]:
346.33132

Related Compounds

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