BS2G Crosslinker disodium

Names

[ CAS No. ]:
881415-72-1

[ Name ]:
BS2G Crosslinker disodium

[Synonym ]:
3-Pyrrolidinesulfonic acid, 1,1'-[(1,5-dioxo-1,5-pentanediyl)bis(oxy)]bis[2,5-dioxo-, disodium salt
Glutaric Acid Bis(3-Sulfo-N-hydroxysuccinimide Ester) Disodium Salt

Biological Activity

[Description]:

BS2G Crosslinker (disodium) is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker

[Target]

Non-cleavable


[In Vitro]

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

[References]

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

Chemical & Physical Properties

[ Molecular Formula ]:
C13H12N2Na2O14S2

[ Molecular Weight ]:
509.37500

[ Exact Mass ]:
508.97800

[ PSA ]:
252.86000

[ Storage condition ]:
-20°C

Related Compounds