A1AT modulator 2

Names

[ Name ]:
A1AT modulator 2

Biological Activity

[Description]:

A1AT modulator 2 (compound 33) is a modulator of A1AT (α-1 antitrypsin) with an IC50 value of ＞1.0 μM and an EC50 value of ＜0.4 μM. A1AT modulator 2 can be used for the research of infection and inflammation[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Others >> Others

Research Areas >> Inflammation/Immunology

[Target]

IC50: ＞1.0 μM (A1AT)[1]

[References]

[1]. Bandarage, Upul Keerthi, et al. Pyrrolo[2,3-f]indazole derivatives as modulators of α-1 antitrypsin and their preparation. US20200361939. 2020.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₇H₂₂FN₃O₃

[ Molecular Weight ]:
455.48

Related Compounds

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