MRGPRX4 modulator-1

Names

[ CAS No. ]:
2492596-61-7

[ Name ]:
MRGPRX4 modulator-1

Biological Activity

[Description]:

MRGPRX4 modulator-1 (compound 31-2) is a potent mas-related g-protein receptor X4 (MRGPR X4) modulator, with antagonist activity of IC50 < 100 nM for MRGPR4. MRGPRX4 modulator-1 can be used for researching MRGPR X4 dependent diseases such as itch, pain, and autoimmune disorders[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Inflammation/Immunology

[Target]

IC50: < 100 nM (MRGPR X4)[1]


[References]

[1]. Adam YEAGER, et al. Modulators of mas-related g-protein receptor x4 and related products and methods. WO2020198537 (compound 31-2).

Chemical & Physical Properties

[ Molecular Formula ]:
C16H13ClF3NO3

[ Molecular Weight ]:
359.73

Related Compounds