Antileishmanial agent-8

Names

[ CAS No. ]:
2477608-96-9

[ Name ]:
Antileishmanial agent-8

Biological Activity

[Description]:

Antileishmanial agent-8 (compound 18) has potent and selective activity against Leishmania donovani (L. donovani) with an IC50 value of 5.64 μM. Antileishmanial agent-8 has relatively low cytotoxicity in L-6 cells (IC50=73.9 μM)[1].

[Related Catalog]:

Research Areas >> Infection

[Target]

IC50: 5.64 μmol/L (L. donovani)[1]


[References]

[1]. Bernal FA, et al. (±)-trans-2-phenyl-2,3-dihydrobenzofurans as leishmanicidal agents: Synthesis, in vitro evaluation and SAR analysis. Eur J Med Chem. 2020;205:112493.

Chemical & Physical Properties

[ Molecular Formula ]:
C18H16O4

[ Molecular Weight ]:
296.32

Related Compounds

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