(D-Ser4,D-Ser(tBu)6,AzaGly10)-LHRH trifluoroacetate salt

Names

[ CAS No. ]:
1926163-39-4

[ Name ]:
(D-Ser4,D-Ser(tBu)6,AzaGly10)-LHRH trifluoroacetate salt

[Synonym ]:
MFCD05663469

Biological Activity

[Description]:

(D-Ser4,D-Ser(tBu)6,Azagly10)-LHRH is an analogue of luteinizing hormone-releasing hormone (LHRH). LHRH plays a central role in the control of reproduction by stimulating the release of pituitary luteinizing hormone (LH) and follicle-stimulating hormone (FSH)[1].

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> GNRH Receptor

Research Areas >> Endocrinology

[References]

[1]. Horvath JE, et al. Effects of long-term treatment with the luteinizing hormone-releasing hormone (LHRH) agonist Decapeptyl and the LHRH antagonist Cetrorelix on the levels of pituitary LHRH receptors and their mRNA expression in rats. Proc Natl Acad Sci U S A. 2002 Nov 12;99(23):15048-53.

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Molecular Formula ]:
C₅₉H₈₄N₁₈O₁₄

[ Molecular Weight ]:
1269.411

[ Exact Mass ]:
1268.641479

[ LogP ]:
-0.95

[ Index of Refraction ]:
1.692