Acetyl-ACTH (3-24) (human, bovine, rat)

Names

[ Name ]:
Acetyl-ACTH (3-24) (human, bovine, rat)

[Synonym ]:
L-Proline, 1-[(2R,8S,11S,14S,17S,20S,23S,26S)-11-[3-[(aminoiminomethyl)amino]propyl]-2-(5-aminopentyl)-20-(2-carboxyethyl)-26-(hydroxymethyl)-17-(1H-imidazol-4-ylmethyl)-8-(1H-indol-3-ylmethyl)-23-[2-(methylthio)ethyl]-1,4,7,10,13,16,19,22,25,28-decaoxo-14-(phenylmethyl)-3,6,9,12,15,18,21,24,27-nonaazanonacos-1-yl]-L-prolyl-L-valylglycyl-L-lysyl-L-lysyl-L-arginyl-L-arginyl-L-prolyl-L-valyl-D-lysyl-L-valyl-L-tyrosyl-
1-{(2R)-2-[(N-Acetyl-L-seryl-L-methionyl-L-α-glutamyl-L-histidyl-L-phenylalanyl-L-arginyl-L-tryptophylglycyl)amino]-7-aminoheptanoyl}-L-prolyl-L-valylglycyl-L-lysyl-L-lysyl-L-arginyl-L-arginyl-L-p rolyl-L-valyl-D-lysyl-L-valyl-L-tyrosyl-L-proline

Biological Activity

[Description]:

Acetyl-ACTH (3-24) (human, bovine, rat) is a fragment of proopiomelanocortin (POMC) peptide. POMC peptides such as adrenocorticotrophin (ACTH), which is the precursor of α-MSH, is also an agonist at the MC-1 receptor[1].

[Related Catalog]:

Research Areas >> Neurological Disease

Signaling Pathways >> Others >> Androgen Receptor

[References]

[1]. K Wakamatsu , et al. Characterisation of ACTH peptides in human skin and their activation of the melanocortin-1 receptor. Pigment Cell Res. 1997 Oct;10(5):288-97.

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Molecular Formula ]:
C₁₂₆H₁₉₈N₃₈O₂₈S

[ Molecular Weight ]:
2725.22

[ Exact Mass ]:
2737.511475

[ LogP ]:
-2.84

[ Index of Refraction ]:
1.674

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.