Lotrafiban hydrochloride

Names

[ CAS No. ]:
179599-82-7

[ Name ]:
Lotrafiban hydrochloride

[Synonym ]:
Lotrafiban hydrochloride
Lotrafiban HCl
UNII-GSV7V79C63

Biological Activity

[Description]:

Lotrafiban hydrochloride is an orally-active platelet GPIIb/IIIa blocker for research of coronary and cerebrovascular disease.

[Related Catalog]:

Research Areas >> Cardiovascular Disease
Signaling Pathways >> Cytoskeleton >> Integrin

[References]

[1]. Topol EJ, Easton D, Harrington RA, et al. Randomized, double-blind, placebo-controlled, international trial of the oral IIb/IIIa antagonist lotrafiban in coronary and cerebrovascular disease. Circulation. 2003;108(4):399-406.  

Chemical & Physical Properties

[ Boiling Point ]:
730ºC at 760 mmHg

[ Molecular Formula ]:
C23H33ClN4O4

[ Molecular Weight ]:
464.99

[ Flash Point ]:
395.3ºC

[ Exact Mass ]:
464.21900

[ PSA ]:
101.98000

[ LogP ]:
2.91020

[ Vapour Pressure ]:
2.27E-22mmHg at 25°C

Related Compounds

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