Kaliotoxin (1-37)

Names

[ Name ]:
Kaliotoxin (1-37)

Biological Activity

[Description]:

Kaliotoxin (1-37) is a toxin from the scorpion Artdroctonus mauretanicus mauretanicus. Kaliotoxin (1-37) is a potent calcium-dependent potassium channel blocker[1].

[Related Catalog]:

Research Areas >> Inflammation/Immunology

Signaling Pathways >> Membrane Transporter/Ion Channel >> Potassium Channel

[In Vitro]

Kaliotoxin (1-37) is homologous with other scorpion toxins such as Charybdotoxin (HY-P0191; ChTX) or Iberiotoxin (HY-P0190; IbTX). Kaliotoxin (1-37) involved in channel blocking by ChTX[1].

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₆₅H₂₇₁N₅₃O₄₈S₈

[ Molecular Weight ]:
4018.82

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Articles

Kaliotoxin, a novel peptidyl inhibitor of neuronal BK-type Ca(2+)-activated K+ channels characterized from Androctonus mauretanicus mauretanicus venom.

J. Biol. Chem. 267 , 1640, (1992)

A peptidyl inhibitor of the high conductance Ca(2+)-activated K+ channels (KCa) has been purified to homogeneity from the venom of the scorpion Androctonus mauretanicus mauretanicus. The peptide has b...

Current views on scorpion toxins specific for K+-channels.

Toxicon 43 , 865-875, (2004)

Much of our knowledge on K+-channels was elucidated using specific peptide ligands isolated from a number of venomous organisms. Recently, this field received a strong support and increased interest d...

Related Compounds

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