FK-739 free base

Names

[ Name ]:
FK-739 free base

[Synonym ]:
2-n-butyl-3-<2'-(1H-tetrazol-5-yl)-4-biphenylylmethyl>-3H-imidazo<4,5-b>pyridine
FK739
2-Butyl-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-3H-imidazo[4,5-b]pyridine
2-butyl-3-[[2'-(1H-tetrazole-5-yl)biphenyl-4-yl]-methyl]imidazo[4,5-b]pyridine
2-butyl-3-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]-3H-imidazo-[4,5-b]pyridine
2-butyl-3-[(2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl]-3H-imidazo[4,5-b]pyridine
FK-739

Biological Activity

[Description]:

FK-739 (free base) is an angiotensin II type 1 (AT1) receptor antagonist used in the study of hypertension[1].

[Related Catalog]:

Research Areas >> Cardiovascular Disease

Signaling Pathways >> GPCR/G Protein >> Angiotensin Receptor

[References]

[1]. Kubo M, et al. Effects of angiotensin II type 1 receptor antagonist on smooth muscle cell phenotype in intramyocardial arteries from spontaneously hypertensive rats. Hypertens Res. 2004 Sep;27(9):685-93.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₄H₂₃N₇

[ Molecular Weight ]:
409.48600

[ Exact Mass ]:
409.20100

[ PSA ]:
85.17000

[ LogP ]:
4.66930

Related Compounds

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