D-Mannitol-13C

Names

[ CAS No. ]:
132202-29-0

[ Name ]:
D-Mannitol-13C

[Synonym ]:
D-Mannitol-1-13C
<1-13C>Mannitol
MFCD00084008
D-Mannitol-1-13C,1,1-d2

Biological Activity

[Description]:

D-Mannitol-13C is the 13C labeled D-Mannitol[1][2][3][4].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Apoptosis
Research Areas >> Cancer
Research Areas >> Metabolic Disease

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

[2]. Tan, K., et al., The mannitol operon repressor MtlR belongs to a new class of transcription regulators in bacteria. J Biol Chem, 2009. 284(52): p. 36670-9.;Nishiyama, A., et al., Mannitol lowers fat digestibility and body fat accumulation in both normal a

Chemical & Physical Properties

[ Melting Point ]:
167-170ºC(lit.)

[ Molecular Formula ]:
C6H14O6

[ Molecular Weight ]:
183.16400

[ Exact Mass ]:
183.08200

[ PSA ]:
121.38000

Safety Information

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds