4-(Trifluoromethyl)aniline-d4

Names

[ CAS No. ]:
1219795-48-8

[ Name ]:
4-(Trifluoromethyl)aniline-d4

[Synonym ]:
Benzen-2,3,5,6-d-amine, 4-(trifluoromethyl)-
4-(Trifluoromethyl)(H)aniline

Biological Activity

[Description]:

4-(Trifluoromethyl)aniline-d4 is deuterium labeled 4-(Trifluoromethyl)aniline. 4-(Trifluoromethyl)aniline is a DYRK1A and DYRK1B kinase inhibitor with IC50s of 54.84 nM and 186.40 nM, respectively[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Protein Tyrosine Kinase/RTK >> DYRK

[References]

[1]. Alicia Foucourt, et al. Design and synthesis of thiazolo[5,4-f]quinazolines as DYRK1A inhibitors, part II. Molecules. 2014 Sep 26;19(10):15411-39.  

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
190.0±40.0 °C at 760 mmHg

[ Molecular Formula ]:
C7H2D4F3N

[ Molecular Weight ]:
165.149

[ Flash Point ]:
86.7±0.0 °C

[ Exact Mass ]:
165.070343

[ LogP ]:
1.95

[ Vapour Pressure ]:
0.6±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.478

Related Compounds

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