Methylmalonic acid-13C4

Names

[ CAS No. ]:
1173019-21-0

[ Name ]:
Methylmalonic acid-13C4

[Synonym ]:
EINECS 200-835-2

Biological Activity

[Description]:

Methylmalonic acid-13C4 is the 13C labeled Methylmalonic acid[1]. Methylmalonic acid (Methylmalonate) is an indicator of Vitamin B-12 deficiency in cancer[2].

[Related Catalog]:

Research Areas >> Cancer

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Vashi P, et al. Methylmalonic Acid and Homocysteine as Indicators of Vitamin B-12 Deficiency in Cancer. PLoS One. 2016 Jan 25;11(1):e0147843.  

Chemical & Physical Properties

[ Molecular Formula ]:
C4H6O4

[ Molecular Weight ]:
119.09704

[ Flash Point ]:
2℃

[ Storage condition ]:
-20°C

Safety Information

[ Symbol ]:

GHS02, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H225-H302 + H332-H319

[ Precautionary Statements ]:
P210-P305 + P351 + P338

[ Hazard Codes ]:
F,Xn

[ Risk Phrases ]:
11-20/21/22-36

[ Safety Phrases ]:
16-36/37

[ RIDADR ]:
UN 1648 3 / PGII

[ WGK Germany ]:
2

Related Compounds