Lanosta-7,9(11),24-trien-3α-hydroxy-26-oic acid

Names

[ CAS No. ]:
111372-80-6

[ Name ]:
Lanosta-7,9(11),24-trien-3α-hydroxy-26-oic acid

[Synonym ]:
(E)-6-((3S,5R,10S,13R,14R)-3-Hydroxy-4,4,10,13,14-pentamethyl-2,3,4,5,6,10,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-methyl-hept-2-enoic acid

Biological Activity

[Description]:

Lanosta-7,9(11),24-trien-3α-hydroxy-26-oic acid, also known as ganoderic acid 24. Lanosta-7,9(11),24-trien-3α-hydroxy-26-oic acid shows high cytotoxicity against cancer cells, such as human lung cancer cells CH27, melanoma cells M21, and oral cancer cells HSC-3[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others

[References]

[1]. Isaka M, et al. Lanostane triterpenes from cultures of the Basidiomycete Ganoderma orbiforme BCC 22324. Phytochemistry. 2013 Mar;87:133-9.  

Chemical & Physical Properties

[ Molecular Formula ]:
C30H46O3

[ Molecular Weight ]:
454.68

[ Exact Mass ]:
454.34500

[ PSA ]:
57.53000

[ LogP ]:
7.31980

Related Compounds

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