Z-Ile-Bt

Names

[ Name ]:
Z-Ile-Bt

[Synonym ]:
Carbamic acid, N-[(1S,2S)-1-(1H-1,2,3-benzotriazol-1-ylcarbonyl)-2-methylbutyl]-, phenylmethyl ester
Benzyl [(2S,3S)-1-(1H-benzotriazol-1-yl)-3-methyl-1-oxo-2-pentanyl]carbamate

Biological Activity

[Description]:

Z-Ile-Bt is an isoleucine derivative[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].

[References]

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Molecular Formula ]:
C₂₀H₂₂N₄O₃

[ Molecular Weight ]:
366.414

[ Exact Mass ]:
366.169189

[ LogP ]:
4.29

[ Index of Refraction ]:
1.620

Safety Information

[ RIDADR ]:
NONH for all modes of transport

Articles

Benzotriazole-mediated syntheses of depsipeptides and oligoesters.

J. Org. Chem. 76 , 4884-4893, (2011)

Reactions of O-Pg(α-hydroxyacyl)benzotriazoles with (a) unprotected α-hydroxycarboxylic acids, (b) amino acids, and (c) amines afforded, respectively, chirally pure (a) oligoesters, (b) depsidipeptide...

Efficient preparation of aminoxyacyl amides, aminoxy hybrid peptides, and alpha-aminoxy peptides.

J. Org. Chem. 74th ed.,, 8690-8694, (2009)

N-(Pg-alpha-aminoxy acids) 1a-g are converted to N-(Pg-alpha-aminoxyacyl)benzotriazoles 2a-g, which react under mild conditions with amines, alpha-amino acids/alpha-dipeptides, and alpha-aminoxy acids...

Abdelmajeid, A.; Tala, S. R.; Amine, M. S.; Katritzky, A. R.

Synthesis , 2995-3005, (2011)