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Tezepelumab

Names

[ CAS No. ]:
1572943-04-4

[ Name ]:
Tezepelumab

Biological Activity

[Description]:

Tezepelumab (AMG 157) is human monoclonal antibody (IgG2λ) that binds specifically to TSLP, blocking it from interacting with its heterodimeric receptor. Tezepelumab can be used for the research of severe, uncontrolled asthma[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Inflammation/Immunology

[Target]

TSLP[1]


[In Vitro]

Tezepelumab 阻断胸腺基质淋巴细胞生成素，一种上皮细胞衍生的细胞因子，与哮喘的发病机理有关[1]。

[References]

[1]. Menzies-Gow A, et, al. Tezepelumab in Adults and Adolescents with Severe, Uncontrolled Asthma. N Engl J Med. 2021 May 13;384(19):1800-1809.  

Chemical & Physical Properties

No Any Chemical & Physical Properties

Related Compounds

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