(±)-Naringenin

Names

[ Name ]:
(±)-Naringenin

[Synonym ]:
Naringenin
(+)-(2R)-naringenin
(R)-naringenin
4',5,7-Trihydroxyflavanone
2,3-dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-4-benzopyrone
(+)-Naringenin
MFCD00006844
5,7-Dihydroxy-2-(4-hydroxyphenyl)chroman-4-one
Naringenine
EINECS 266-769-1

Biological Activity

[Description]:

(±)-Naringenin is a naturally-occurring flavonoid. (±)-Naringenin displays vasorelaxant effect on endothelium-denuded vessels via the activation of BKCa channels in myocytes[1].

[Related Catalog]:

Research Areas >> Cardiovascular Disease

Signaling Pathways >> Membrane Transporter/Ion Channel >> Potassium Channel

[References]

[1]. Saponara S, et al. (+/-)-Naringenin as large conductance Ca(2+)-activated K+ (BKCa) channel opener in vascular smooth muscle cells. Br J Pharmacol. 2006 Dec;149(8):1013-21.

Chemical & Physical Properties

[ Density]:
1.485g/cm3

[ Boiling Point ]:
577.5ºC at 760mmHg

[ Melting Point ]:
247-250 °C(lit.)

[ Molecular Formula ]:
C₁₅H₁₂O₅

[ Molecular Weight ]:
272.25300

[ Exact Mass ]:
272.06800

[ PSA ]:
83.83000

[ LogP ]:
2.13750

[ Storage condition ]:
0-6°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38:Irritating to eyes, respiratory system and skin .

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
DJ2981530

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