6-Dehydroprogesterone

Names

[ Name ]:
6-Dehydroprogesterone

[Synonym ]:
4,6-pregnadiene-3,20-dione
pregna-4,6-diene-2,30-dione
Dehydroprogesterone
MFCD00199858
4,6-PREGNADIEN-3,20-DIONE
CIS-DYDROGESTERONE
Dydrogesterone impurity B
6-Dehydroprogesterone
Pregna-4,6-diene-3,20-dione
6,7-Didehydroprogesterone

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
462.8±45.0 °C at 760 mmHg

[ Melting Point ]:
146 °C

[ Molecular Formula ]:
C₂₁H₂₈O₂

[ Molecular Weight ]:
312.446

[ Flash Point ]:
172.2±25.7 °C

[ Exact Mass ]:
312.208923

[ PSA ]:
34.14000

[ LogP ]:
3.58

[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C

[ Index of Refraction ]:
1.557

Safety Information

[ HS Code ]:
2937190090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2937190090

Articles

Coagulation and fibrynolitic parameters in women and the effects of hormone therapy; comparison of transdermal and oral administration.

Gynecol. Endocrinol. 29(2) , 165-8, (2013)

It is established that hormone therapy (HT) is related with significant increased prothrombotic risk factor. The aim of our study was to assess the effects of oral hormone therapy (o-HT) and transderm...

Oral estradiol and dydrogesterone combination therapy in postmenopausal women: review of efficacy and safety.

Maturitas 76(1) , 10-21, (2013)

HRT is known to be effective for the relief of menopausal symptoms and prevention of osteoporosis. HRT should be tailored to the woman, enhancing the beneficial effects of the treatment while minimizi...

Hormone replacement therapy regimens in chemotherapy-induced premature ovarian failure and the subsequent correction of hormone levels.

Neuro Endocrinol. Lett. 33(7) , 697-702, (2012)

Premature ovarian failure (POF) is a consequence of gonadotoxic chemoradiotherapy given in antyneoplasia treatment. In young women it will correlate with menopausal symptoms which tend to appear due t...