4-Bromo-2,6-dimethylphenol

Names

[ Name ]:
4-Bromo-2,6-dimethylphenol

[Synonym ]:
4-BROMO-2,6-XYLENOL
4-Bromo-2,6-dimethylphenol
4-Brom-2,6-dimethylphenol
EINECS 219-153-1
2,6-Dimethyl-4-bromophenol
MFCD00002314
4-bromo-6-xylenol
Phenol, 4-bromo-2,6-dimethyl-
4-bromo-2,6-dimethyl-phenol
4-Br-2,6-Me2C6H2OH

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
253.0±35.0 °C at 760 mmHg

[ Melting Point ]:
74-78 °C(lit.)

[ Molecular Formula ]:
C₈H₉BrO

[ Molecular Weight ]:
201.061

[ Flash Point ]:
106.8±25.9 °C

[ Exact Mass ]:
199.983673

[ PSA ]:
20.23000

[ LogP ]:
3.41

[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.580

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: ZE6780000

CHEMICAL NAME :: 2,6-Xylenol, 4-bromo-

CAS REGISTRY NUMBER :: 2374-05-2

BEILSTEIN REFERENCE NO. :: 1862399

LAST UPDATED :: 199701

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C8-H9-Br-O

MOLECULAR WEIGHT :: 201.08

WISWESSER LINE NOTATION :: QR DE B1 F1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 650 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JMPCAS Journal of Medicinal and Pharmaceutical Chemistry. (Washington, DC) V.1-5, 1959-62. For publisher information, see JMCMAR. Volume(issue)/page/year: 2,201,1960

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S37/39

[ RIDADR ]:
UN 2811 6.1/PG 3

[ WGK Germany ]:
3

[ RTECS ]:
ZE6780000

[ HS Code ]:
2908199090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2908199090

[ Summary ]:
HS: 2908199090. derivatives of polyphenols or phenol-alcohols containing only halogen substituents and their salts. VAT:17.0%. tax rebate rate:9.0%. supervision conditions:None. MFN tariff:5.5%. general tariff:30.0%

Articles

Effect of gradient steepness on the kinetic performance limits and peak compression for reversed-phase gradient separations of small molecules.

J. Chromatogr. A. 1409 , 152-8, (2015)

The effect of gradient steepness on the kinetic performance limits and peak compression effects has been assessed in gradient mode for the separation of phenol derivatives using columns packed with 2....

Polymerization of Three Bromo-2, 6-xylenols in THF Solution. Semsarzadeh MA and Price C.

Macromolecules 10(2) , 482-5, (1977)

Spontaneous rearrangement of o-quinobromides. Ershov VV and Volod'kin AA.

Russ. Chem. Bull. 14(2) , 313-8, (1965)