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Isobutyraldehyde

Names

[ CAS No. ]:
78-84-2

[ Name ]:
Isobutyraldehyde

[Synonym ]:
Isobutaldehyde
isobutyral
EINECS 201-149-6
Isobutyraldehyde
iso-C3H7CHO
α-Methylpropionaldehyde
FEMA 2220
1-keto-2-methylpropane
2-Methylpropanal
isobutyric
2-methylpropan-1-al
2-methyl-1-propanal
iso-Butanal
MFCD00006980
methylpropanal
valinealdehyde
2-METHYL-PROPANAL
Propanal, 2-methyl-
isobutyric aldehyde
2-methyl-propionaldehyde

Chemical & Physical Properties

[ Density]:
0.8±0.1 g/cm3

[ Boiling Point ]:
67.1±8.0 °C at 760 mmHg

[ Melting Point ]:
−65 °C(lit.)

[ Molecular Formula ]:
C4H8O

[ Molecular Weight ]:
72.106

[ Flash Point ]:
-18.9±0.0 °C

[ Exact Mass ]:
72.057518

[ PSA ]:
17.07000

[ LogP ]:
0.72

[ Vapour density ]:
2.5 (vs air)

[ Vapour Pressure ]:
147.4±0.1 mmHg at 25°C

[ Index of Refraction ]:
1.367

[ Stability ]:
Stable. Refrigerate. Highly flammable. Incompatible with strong oxidizing agents, strong bases, strong acids, strong reducing agents.

[ Water Solubility ]:
75 g/L (20 ºC)

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
NQ4025000
CHEMICAL NAME :
Isobutyraldehyde
CAS REGISTRY NUMBER :
78-84-2
LAST UPDATED :
199806
DATA ITEMS CITED :
13
MOLECULAR FORMULA :
C4-H8-O
MOLECULAR WEIGHT :
72.12
WISWESSER LINE NOTATION :
VHY1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Open irritation test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 11/3/1971 ** ACUTE TOXICITY DATA **
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
960 mg/kg
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - other changes Gastrointestinal - necrotic changes Blood - hemorrhage
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 37(5),104,1972
TYPE OF TEST :
LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
8000 ppm/4H
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine. (Chicago, IL) V.2-10, 1950-54. For publisher information, see AEHLAU. Volume(issue)/page/year: 10,61,1954
TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
39500 mg/m3/2H
TOXIC EFFECTS :
Behavioral - excitement Sense Organs and Special Senses (Eye) - effect, not otherwise specified Lungs, Thorax, or Respiration - pleural thickening
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 37(5),104,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
7130 uL/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine. (Chicago, IL) V.2-10, 1950-54. For publisher information, see AEHLAU. Volume(issue)/page/year: 10,61,1954 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 5 mg/m3;Skin JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 84782 No. of Facilities: 21 (estimated) No. of Industries: 1 No. of Occupations: 3 No. of Employees: 705 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 84782 No. of Facilities: 32 (estimated) No. of Industries: 3 No. of Occupations: 2 No. of Employees: 4114 (estimated) No. of Female Employees: 655 (estimated)

Safety Information

[ Symbol ]:

GHS02, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H225-H319

[ Precautionary Statements ]:
P210-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US)

[ Hazard Codes ]:
F:Flammable

[ Risk Phrases ]:
R11;R22

[ Safety Phrases ]:
S16-S36/37-S9-S33-S29

[ RIDADR ]:
UN 2045 3/PG 2

[ WGK Germany ]:
1

[ RTECS ]:
NQ4025000

[ Packaging Group ]:
II

[ Hazard Class ]:
3

[ HS Code ]:
2912190090

Synthetic Route

Precursor & DownStream

Customs

[ HS Code ]: 2912190090

[ Summary ]:
2912190090 acyclic aldehydes without other oxygen function。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

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