Tosylmethyl isocyanide
Names
[ CAS No. ]:
36635-61-7
[ Name ]:
Tosylmethyl isocyanide
[Synonym ]:
TosMICTosylmethyl Isocyanide
4-toluene-sulfonylmethyl isocyanide
(p-Tolylsulfonyl)methyl isocyanide
Tosylmethy isocyanide
Tosylmethylisocyanide
Isocyanomethyl 4-methylphenyl sulfone
Benzene, 1-((isocyanomethyl)sulfonyl)-4-methyl-
p-Toluenesulfonylmethyl isocyanide
1-[(Isocyanomethyl)sulfonyl]-4-methylbenzene
4-Toluenesulfonylmethyl isocyanide
P-tolysulfonylmethylisocyanide
p-tosylmethyl isocyanide
4-Toluenesulfonylmethylisocyanide
TOSMIC
EINECS 253-140-1
p-Toluenesulfonyl Isocyanide
Tosylmethyl isocyani
MFCD00000005
Benzene, 1-[(isocyanomethyl)sulfonyl]-4-methyl-
IsocyanoMethyl p-Tolyl Sulfone
1-[(Isocyanmethyl)sulfonyl]-4-methylbenzol
4-Toluenesulphonylmethyl Isocyanide
Chemical & Physical Properties
[ Density]:
1.24 g/cm3
[ Boiling Point ]:
400.9ºC at 760 mmHg
[ Melting Point ]:
109-113 °C(lit.)
[ Molecular Formula ]:
C9H9NO2S
[ Molecular Weight ]:
195.238
[ Flash Point ]:
196.3ºC
[ Exact Mass ]:
195.035400
[ PSA ]:
42.52000
[ LogP ]:
1.95700
[ Storage condition ]:
-20°C
[ Water Solubility ]:
insoluble
MSDS
Safety Information
[ Symbol ]:
GHS06
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H301 + H311 + H331
[ Precautionary Statements ]:
P261-P280-P301 + P310-P311
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
[ Hazard Codes ]:
T:Toxic
[ Risk Phrases ]:
R23/24/25
[ Safety Phrases ]:
S36/37-S45-S38-S36/37/39-S28A
[ RIDADR ]:
UN 2811 6.1/PG 3
[ WGK Germany ]:
3
[ Packaging Group ]:
III
[ Hazard Class ]:
6.1(b)
[ HS Code ]:
29299000
Customs
[ HS Code ]: 2926909090
[ Summary ]:
HS:2926909090 other nitrile-function compounds VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%
Articles
Bioorg. Med. Chem. Lett. 15(16) , 3717-9, (2005)
A convenient method for the synthesis of 1,5-disubstituted imidazoles has been developed on a polymeric support using base-promoted 1,3-dipolar cycloaddition reaction of p-toluenesulfonylmethyl isocya...
Synthesis of novel triplet drugs with 1,3,5-trioxazatriquinane skeletons and their pharmacologies. Part 2: Synthesis of novel triplet drugs with the epoxymethano structure (capped homotriplet).Bioorg. Med. Chem. Lett. 21(20) , 6198-202, (2011)
An improved synthetic method for triplet drugs with the 1,3,5-trioxazatriquinane skeleton was developed that used p-toluenesulfonylmethyl isocyanide (TosMIC) instead of 1,3-dithiane. Using the improve...
Alkyl and aromatic isocyanide binding to haem complexes.Biochem. J. 262(3) , 959-63, (1989)
Equilibrium constants for the binding of ethyl (EIC), n-butyl (BIC), p-toluenesulphonylmethyl (TMIC) and 2,6-dimethylphenyl isocyanides (DIMPI) to an imidazole-haem complex in toluene and aqueous dete...