DMT
Names
[ CAS No. ]:
120-61-6
[ Name ]:
DMT
[Synonym ]:
1,4-Benzenedicarboxylic acid, dimethyl ester
METHYL TEREPHTHALATE
EINECS 204-411-8
1,4-DIMETHYL PHTHALATE
Terephthalic Acid Dimethyl Ester
Dimethyl terephthalate
DMT
MFCD00008440
TEREPHTHALIC ACID METHYL ESTER
dimethyl benzene-1,4-dicarboxylate
DIMETHYL P-PHTHALATE
TEREPHTHARIC ACID DIMETHYL ESTER
Chemical & Physical Properties
[ Density]:
1.2±0.1 g/cm3
[ Boiling Point ]:
285.0±8.0 °C at 760 mmHg
[ Melting Point ]:
140 °C
[ Molecular Formula ]:
C10H10O4
[ Molecular Weight ]:
194.184
[ Flash Point ]:
148.0±7.9 °C
[ Exact Mass ]:
194.057907
[ PSA ]:
52.60000
[ LogP ]:
2.47
[ Vapour density ]:
1.04 (vs air)
[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C
[ Index of Refraction ]:
1.515
[ Stability ]:
Stable. Incompatible with strong acids, strong bases, strong oxidizing agents.
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- WZ1225000
- CHEMICAL NAME :
- Terephthalic acid, dimethyl ester
- CAS REGISTRY NUMBER :
- 120-61-6
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 17
- MOLECULAR FORMULA :
- C10-H10-O4
- MOLECULAR WEIGHT :
- 194.20
- WISWESSER LINE NOTATION :
- 1OVR DVO1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >3200 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 3900 mg/kg
- TOXIC EFFECTS :
- Behavioral - muscle weakness
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- >5 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 57600 mg/kg/14W-C
- TOXIC EFFECTS :
- Nutritional and Gross Metabolic - weight loss or decreased weight gain
- TYPE OF TEST :
- TCLo - Lowest published toxic concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1 mg/m3/2H/22W-I
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Olfaction) - effect, not otherwise specified Vascular - BP lowering not characterized in autonomic section Nutritional and Gross Metabolic - weight loss or decreased weight gain
MUTATION DATA
- TEST SYSTEM :
- Rodent - mouse
- DOSE/DURATION :
- 200 umol/kg
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 204,703,1988 *** REVIEWS *** TOXICOLOGY REVIEW BPCT** Progress Report from the Environmental Protection Agency to NIOSH on Benzenepolycarboxylates, 1974 Volume(issue)/page/year: -,183,1974 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 0.1 mg/m3 JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83502 No. of Facilities: 58 (estimated) No. of Industries: 5 No. of Occupations: 7 No. of Employees: 993 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83502 No. of Facilities: 104 (estimated) No. of Industries: 3 No. of Occupations: 3 No. of Employees: 2467 (estimated) No. of Female Employees: 204 (estimated)
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ Hazard Codes ]:
Xi
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S24/25
[ RIDADR ]:
3256
[ WGK Germany ]:
1
[ RTECS ]:
WZ1225000
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Articles
Mater. Sci. Eng. C. Mater. Biol. Appl. 53 , 15-22, (2015)
In this work, we present new nanocomposite materials derived from segmented copolyesters, comprising ethylene terephthalate (PET) segments and dimerized linoleic acid (DLA), and nanometric cerium oxid...
Lack of androgenicity and estrogenicity of the three monomers used in Eastman’s Tritan™ copolyestersFood Chem. Toxicol. 50(6) , 2196-205, (2012)
Highlights ► Androgenicity and estrogenicity assessed with QSAR and in vitro, in vivo assays. ► Assessments for androgenicity and estrogenicity were universally negative. ► Data suggest no androgenic ...
Comparison of initial hydrolysis of the three dimethyl phthalate esters (DMPEs) by a basidiomycetous yeast, Trichosporon DMI-5-1, from coastal sediment.Environ. Sci. Pollut. Res. Int. 18(9) , 1653-60, (2011)
Dimethyl phthalate esters (DMPEs) are a group of plasticizers commonly detected in the environment with potential adverse human health impact. The degradation of DMPEs by fungal systems has been studi...