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SMN2 splicing modulator TEC-1

Product detail:

Published date: 2024-07-17 15:06:27

CAS number: 2407723-70-8

Name: SMN2 splicing modulator TEC-1

Price:
$550.0/5mg

Purity: 98.0%

Stocking period: 3 Day

Stock: 3

Product Webpage: https://www.dcchemicals.com/product_show-smn2splicingmodulatortec-1.html

Detail Product Information:
SMN2 splicing modulator TEC-1 is a novel specific, CNS penetrant small molecule SMN2 splicing modulator, increases the expression level of FL-SMN2 mRNA and decreases the expression level of Δ7 mRNA.TEC-1 showed higher selectively (>60-fold) on galactosylceramidase and huntingtin gene expression compared to previously reported compounds (e.g., SMN-C3) due to off-target effects on cryptic exon inclusion and nonsense-mediated mRNA decay.TEC-1 modulates SMN2 splicing and displays disease-modifying effects in motor neurons derived from SMA patient iPSCs (GM24468).|TEC-1 rescues the phenotype in a murine model of spinal muscular atrophy (SMA).

Supplier/Manufacture:

Name: DC Chemicals Limited Recommended

Chemsrc Level: Verified

Product #: 34963

Tel: 58447131

Address: Jinyu Rd100, pudong

Area: China(Mainland)

Contact: Tony Cao

Contact Phone #: 13564518121

Email: sales@dcchemicals.com

Website: http://www.dcchemicals.com

Major Market:

Foreign Trade % of Salers:

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Detail introduction:
D&C Chemicals provides a wide range of research chemicals and biochemicals including novel life-science reagents, reference compounds, APIs and Natural compounds for laboratory and scientific use.



D&C Chem has established a global network of thousands of customers from many research centers and Reagent companies in the USA, Europe and Japan.

We are the the official vendor of more than 500 universities and institutes including: Harvard University,Yale University,NIH/NCI, City of Hope ORG, PARTNERS ORG,John Hopkins University,Universit tsklinikum,Oxford University,Newcastle University,UNC,UCSF and many other universities and institutes. Our bioactive compounds received good feedback from our customers.





Our credo is committed to the adoption of different products, reliable quality, competitive prices and quality service to create value for customers.

Top suppliers:

Name: Shanghai Nianxing Industrial Co., Ltd

Area: China

Price:
$550.0/5mg

Contact: Yang

Product Detail: SMN2 splicing modulator TEC-1


Name: DC Chemicals Limited

Area: China

Price:
$550.0/5mg

Contact: Tony Cao

Product Detail: SMN2 splicing modulator TEC-1


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2024-07-17 SMN2 splicing modulator TEC-1

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