<Suppliers Price>

Gomisin D

Names

[ CAS No. ]:
60546-10-3

[ Name ]:
Gomisin D

[Synonym ]:
(11S,12R,15S,24S,25S)-12,25-Dihydroxy-18,19,20-trimethoxy-11,12,24,25-tetramethyl-4,6,9,14-tetraoxapentacyclo[13.7.3.0.0.0]pentacosa-1(22),2,7,16,18,20-hexaen-13-one
(11R,12R,15S,24S,25S)-12,25-Dihydroxy-18,19,20-trimethoxy-11,12,24,25-tetramethyl-4,6,9,14-tetraoxapentacyclo[13.7.3.0.0.0]pentacosa-1(22),2,7,16,18,20-hexaen-13-one
10,15-Propano-10H-1,3,4,9-tetraoxabenzo[3,4]cycloundec[1,2-e]inden-8(5H)-one, 6,7-dihydro-7,19-dihydroxy-12,13,14-trimethoxy-6,7,18,19-tetramethyl-, (6S,7R,10S,18S,19S)-
10,15-Propano-10H-1,3,4,9-tetraoxabenzo[3,4]cycloundec[1,2-e]inden-8(5H)-one, 6,7-dihydro-7,19-dihydroxy-12,13,14-trimethoxy-6,7,18,19-tetramethyl-, (6R,7R,10S,18S,19S)-
Gomisin D

Biological Activity

[Description]:

Gomisin D, a lignan compound isolated from Fructus Schisandra, is a potential antidiabetic and anti-Alzheimer’s agent. Gomisin D inhibits UDP-Glucuronosyltransferases activity and scavenges ABTS(+) radicals. Gomisin D is used as a quality marker of Shengmai San and shenqi Jiangtang Granule[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Metabolic Disease

[Target]

UDP-Glucuronosyltransferases[1]


[References]

[1]. Zheng X, et al. A Rapid UPLC-MS Method for Quantification of Gomisin D in Rat Plasma and Its Application to a Pharmacokinetic and Bioavailability Study. Molecules. 2019 Apr 10;24(7).

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
698.5±55.0 °C at 760 mmHg

[ Melting Point ]:
194ºC

[ Molecular Formula ]:
C28H34O10

[ Molecular Weight ]:
530.564

[ Flash Point ]:
229.3±25.0 °C

[ Exact Mass ]:
530.215210

[ PSA ]:
122.14000

[ LogP ]:
3.95

[ Vapour Pressure ]:
0.0±2.3 mmHg at 25°C

[ Index of Refraction ]:
1.561

[ Storage condition ]:
2-8℃

Related Compounds