Published date: 2021-04-01 19:25:19
CAS number: 142217-69-4
Name: Entecavir
Price:
$Inquiry/1kg
Purity: 99.9%
Stocking period: Inquiry
Stock: In Stock
Detail Product Information:
Names
[ Name ]: entecavir (anhydrous)
[ Synonym ]: More Synonyms
Chemical & Physical Properties
[ Density ]: 1.8±0.1 g/cm3
[ Boiling Point ]: 734.2ºC at 760 mmHg
[ Melting Point ]: 249-252ºC
[ Molecular Formula ]: C12H15N5O3
[ Molecular Weight ]: 277.279
[ Flash Point ]: 397.9ºC
[ Exact Mass ]: 277.117493
[ PSA ]: 130.05000
[ LogP ]: -0.96
[ Index of Refraction ]: 1.837
MSDS
Material Safety Data Sheet
Section1. Identification of the substance
Product Name: Entecavir
Synonyms:
Section2. Hazards identification
Harmful by inhalation, in contact with skin, and if swallowed.
Section3. Composition/information on ingredients.
Ingredient name:Entecavir
CAS number:142217-69-4
Section4. First aid measures
Skin contact:Immediately wash skin with copious amounts of water for at least 15 minutes while removing
contaminated clothing and shoes. If irritation persists, seek medical attention.
Eye contact:Immediately wash skin with copious amounts of water for at least 15 minutes. Assure adequate
flushing of the eyes by separating the eyelids with fingers. If irritation persists, seek medical
attention.
Inhalation:Remove to fresh air. In severe cases or if symptoms persist, seek medical attention.
Ingestion:Wash out mouth with copious amounts of water for at least 15 minutes. Seek medical attention.
Section5. Fire fighting measures
In the event of a fire involving this material, alone or in combination with other materials, use dry
powder or carbon dioxide extinguishers. Protective clothing and self-contained breathing apparatus
should be worn.
Section6. Accidental release measures
Personal precautions: Wear suitable personal protective equipment which performs satisfactorily and meets local/state/national
standards.
Respiratory precaution:Wear approved mask/respirator
Hand precaution:Wear suitable gloves/gauntlets
Skin protection:Wear suitable protective clothing
Eye protection:Wear suitable eye protection
Methods for cleaning up: Mix with sand or similar inert absorbent material, sweep up and keep in a tightly closed container
for disposal. See section 12.
Environmental precautions: Do not allow material to enter drains or water courses.
Section7. Handling and storage
Handling:This product should be handled only by, or under the close supervision of, those properly qualified
in the handling and use of potentially hazardous chemicals, who should take into account the fire,
health and chemical hazard data given on this sheet.
Storage:Store in closed vessels, refrigerated.
Section8. Exposure Controls / Personal protection
Engineering Controls: Use only in a chemical fume hood.
Personal protective equipment: Wear laboratory clothing, chemical-resistant gloves and safety goggles.
General hydiene measures: Wash thoroughly after handling. Wash contaminated clothing before reuse.
Section9. Physical and chemical properties
Appearance:Not specified
Boiling point:No data
Melting point:No data
Flash point:No data
Density:No data
Molecular formula: C12H15N5O3
Molecular weight: 277.3
Section10. Stability and reactivity
Conditions to avoid: Heat, flames and sparks.
Materials to avoid: Oxidizing agents.
Possible hazardous combustion products: Carbon monoxide, nitrogen oxides.
Section11. Toxicological information
No data.
Section12. Ecological information
No data.
Section13. Disposal consideration
Arrange disposal as special waste, by licensed disposal company, in consultation with local waste
disposal authority, in accordance with national and regional regulations.
Section14. Transportation information
Non-harzardous for air and ground transportation.
Section15. Regulatory information
No chemicals in this material are subject to the reporting requirements of SARA Title III, Section
302, or have known CAS numbers that exceed the threshold reporting levels established by SARA
Title III, Section 313.
SECTION 16 - ADDITIONAL INFORMATION
N/A
Safety Information
[ RIDADR ]: NONH for all modes of transport
[ HS Code ]: 2933990090
Synthetic RoutePrevious 1/19 Next
6-chloroentecavir
701278-58-2
6-chloroentecav...
~71%
Entecavir
142217-69-4
Entecavir
Literature: HANMI HOLDINGS CO., LTD. Patent: US2011/251387 A1, 2011 ; Location in patent: Page/Page column 8 ;
tert-butyl (6-iodo-9-((4aR,6S,7aS)-2-methyl-5-methylenehexahydrocyclopenta[d][1,3]dioxin-6-yl)-9H-purin-2-yl)carbamate
1328921-77-2
tert-butyl (6-i...
~88%
Entecavir
142217-69-4
Entecavir
Literature: ScinoPharm Taiwan, Ltd. Patent: US2011/201809 A1, 2011 ; Location in patent: Page/Page column 18 ;
6-(benzyloxy)-9-((4aR,6S,7aS)-5-methylene-2-phenylhexahydrocyclopenta[d][1,3]dioxin-6-yl)-N-(trimethylsilyl)-9H-purin-2-amine
1351691-93-4
6-(benzyloxy)-9...
~86%
Entecavir
142217-69-4
Entecavir
Literature: ALPHORA RESEARCH INC.; ALBERICO, Dino; CLAYTON, Joshua; DIXON, Craig; GORIN, Boris Patent: WO2011/150512 A1, 2011 ; Location in patent: Page/Page column 11 ;
Precursor & DownStream
Precursor 4
6-chloroentecavir Structure CAS#:701278-58-2
6-chloroentecavir
6-(benzyloxy)-9-((4aR,6S,7aS)-5-methylene-2-phenylhexahydrocyclopenta[d][1,3]dioxin-6-yl)-N-(trimethylsilyl)-9H-purin-2-amine Structure CAS#:1351691-93-4
6-(benzyloxy)-9...
9-[(1S,3R,4S)-4-tert-butyldimethylsilyloxy-3-(tert-butyldimethylsilyloxymethyl)-2-methylene-cyclopentyl]-6-chloro-9H-purine-2-carbamic acid tert-butyl ester Structure CAS#:1354715-15-3
9-[(1S,3R,4S)-4...
6-chloro-9-[(1S,3R,4S)-4-hydroxy-3-hydroxymethyl-2-methylene-cyclopentyl]-N-(tert-butyloxycarbonyl)-9H-purine-2-carbamic acid tert-butyl ester Structure CAS#:1354715-31-3
6-chloro-9-[(1S...
DownStream 0
Customs
[ HS Code ]: 2933990090
[ Summary ]: 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
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Synonyms
2-Amino-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-1,9-dihydro-6H-purin-6-one
entecavir (anhydrous)
6H-Purin-6-one, 2-amino-1,9-dihydro-9-((1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl)-
2-amino-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylidenecyclopentyl]-3H-purin-6-one
2-amino-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylidenecyclopentyl]-1,9-dihydro-6H-purin-6-one
6H-Purin-6-one, 2-amino-1,9-dihydro-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-
Baraclude
entecavir
9H-purin-6-ol, 2-amino-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-
UNII-NNU2O4609D
2-amino-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylidenecyclopentyl]-9H-purin-6-ol
Name: JINAN DEPTONS CHEMICALl TECHNOLOGY CO. LTD
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Product #: 160
Tel: 0532-80919617
Address: Room A408, no. 750, ShunHua Road, High-Tech Zone, Jinan city
Area: China(Mainland)
Contact: Angela
Contact Phone #: 18153243071
Email: bdlzhipin@aliyun.com
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Name: Shanghai Nianxing Industrial Co., Ltd
Area: China
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Area: China
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Product Detail: Entecavir
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Area: China
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