4-Nitrophthalimide
Names
[ CAS No. ]:
89-40-7
[ Name ]:
4-Nitrophthalimide
[Synonym ]:
4-Nitrophthalimide
4-nitro-phthalimid
5-NITROPHTHALIMIDE
4-Nitrophtalimide
5-Nitro-1H-isoindole-1,3(2H)-dione
3-nitrophthalimide
4-Nirtophthalimide
5-Nitroisoindoline-1,3-dione
5-Nitro-isoindolin-1,3-dion
4-nitro-phthalimide
5-nitrosoindoline-1,3-dione
EINECS 201-905-5
5-nitro-isoindole-1,3-dione
P-NITRO-PHTHALIMIDE
PHTHALIMIDE,4-NITRO
MFCD00005884
Chemical & Physical Properties
[ Density]:
1.6±0.1 g/cm3
[ Melting Point ]:
206 °C
[ Molecular Formula ]:
C8H4N2O4
[ Molecular Weight ]:
192.128
[ Exact Mass ]:
192.017105
[ PSA ]:
91.99000
[ LogP ]:
0.88
[ Index of Refraction ]:
1.658
[ Stability ]:
Stable. Combustible. Incompatible with moisture, water, strong oxidising agents, strong bases.
[ Water Solubility ]:
<0.01 g/100 mL at 18 ºC
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TI5625000
- CHEMICAL NAME :
- Phthalimide, 4-nitro-
- CAS REGISTRY NUMBER :
- 89-40-7
- BEILSTEIN REFERENCE NO. :
- 0180224
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C8-H4-N2-O4
- MOLECULAR WEIGHT :
- 192.14
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
MUTATION DATA
- TYPE OF TEST :
- Mutation in microorganisms
- TEST SYSTEM :
- Bacteria - Salmonella typhimurium
- DOSE/DURATION :
- 333 ug/plate
- REFERENCE :
- EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 11(Suppl 12),1,1988
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xi:Irritant;
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S37/39-S26
[ RIDADR ]:
NONH for all modes of transport
[ RTECS ]:
TI5625000
[ HS Code ]:
2925190090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2925190090
[ Summary ]:
2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%
Articles
Mutagenesis 8(3) , 257-64, (1993)
A method is described for using the fragments identified by the CASE structure-activity relational expert system to identify the type of chemicals that require further testing in mutagenicity and clas...
Colorimetric detection of achiral anions and chiral carboxylates by a chiral thiourea-phthalimide dyad.Photochem. Photobiol. Sci. 9(10) , 1385-90, (2010)
The chiral chemosensor 1, based on a thiourea-activated phthalimide, is available by four reaction steps from 4-nitrophthalimide. 1 detects fluoride, chloride, acetate, and dihydrogen phosphate anions...
Design, synthesis and protection against pentylenetetrazole-induced seizure of N-aryl derivatives of the phthalimide pharmacophore.Med. Chem. 8(5) , 953-63, (2012)
A series of compounds including N-aryl substituents of phthalimide and 4-nitrophthalimide were synthesized and evaluated for their anticonvulsant properties. The in vivo screening data suggest that al...