2-(Hydroxymethyl)isoindoline-1,3-dione
Names
[ CAS No. ]:
118-29-6
[ Name ]:
2-(Hydroxymethyl)isoindoline-1,3-dione
[Synonym ]:
2-(Hydroxymethyl)-1H-isoindole-1,3(2H)-dione
PHTHALIMIDOMETHANOL
phthalimidomethyl alcohol
oxymethylphthalimide
N-(Hydroxymethyl)phthalimide
N-Hydroxymethylphthalimide
Phthalimidylmethanol
Hydroxymethyl Phthalimide
Methanol,phthalimido
AURORA KA-454
IFLAB-BB F0777-0575
N-Methylolphthalimide
MFCD00005899
EINECS 204-241-4
Chemical & Physical Properties
[ Density]:
1.5±0.1 g/cm3
[ Boiling Point ]:
332.0±25.0 °C at 760 mmHg
[ Melting Point ]:
147-149 °C(lit.)
[ Molecular Formula ]:
C9H7NO3
[ Molecular Weight ]:
177.157
[ Flash Point ]:
154.6±23.2 °C
[ Exact Mass ]:
177.042587
[ PSA ]:
57.61000
[ LogP ]:
0.76
[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C
[ Index of Refraction ]:
1.644
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TI5270000
- CHEMICAL NAME :
- Phthalimide, N-(hydroxymethyl)-
- CAS REGISTRY NUMBER :
- 118-29-6
- BEILSTEIN REFERENCE NO. :
- 0140946
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C9-H7-N-O3
- MOLECULAR WEIGHT :
- 177.17
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Unreported
- DOSE :
- 300 mg/kg
- SEX/DURATION :
- female 13 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Effects on Embryo or Fetus - fetal death
- REFERENCE :
- GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 48(10),64,1983
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ Hazard Codes ]:
Xi
[ Safety Phrases ]:
S22-S24/25
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
TI5270000
[ HS Code ]:
29251995
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2925190090
[ Summary ]:
2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%
Articles
Carbohydr. Res. 342(9) , 1169-74, (2007)
3,4,6-Tri-O-acetyl-D-galactal, 3,4,6-tri-O-acetyl-D-glucal and 3,6,2',3',4'6'-hexa-O-acetyl-D-lactal were reacted with N-hydroxymethylphthalimide and boron trifluoride etherate to produce the correspo...
Aqueous degradation of N-(hydroxymethyl)phthalimide in the presence of specific and general bases. Kinetic assessment of N-hydroxymethyl derivatives of nitrogen heterocycles as possible prodrugs.J. Pharm. Biomed. Anal. 7(6) , 685-91, (1989)
The conversion of N-(hydroxymethyl)phthalimide (NHPH) to phthalimide could not be detected within 300 s at pH 9.0, whereas in 0.18 M NaOH complete conversion of NHPH to phthalimide was observed within...
[Effect of hydroxymethylphthalimide on embryogenesis in white rats].Gig. Sanit. (10) , 64-6, (1983)