Demethyl tetrandrine

Names

[ Name ]:
Demethyl tetrandrine

[Synonym ]:
(S,S)-(+)-tetrandine
(1β)-6,6',12-Trimethoxy-2,2'-dimethylberbaman-7-ol
Fangquinoline
6,6',12-Trimethoxy-2,2'-dimethylberbaman-7-ol
N1799
I06-1344
THALRUGOSINE
FF-0018
Fangchinoline
d,l-Fangchinolin

Biological Activity

[Description]:

(R)-Fangchinoline (Thalrugosine), a alkaloids from genus Stephania，exhibits antimicrobial and hypotensive activity. The roots and stems of several plants from genus Stephania are all used as traditional Chinese medicine and have been used for treatment of fever, diarrhea, dyspepsia and urinary disease[1].

[Related Catalog]:

Research Areas >> Cardiovascular Disease

Signaling Pathways >> Others >> Others

Research Areas >> Inflammation/Immunology

[References]

[1]. Xiao J, et al. Rapid characterization of TCM Qianjinteng by UPLC-QTOF-MS and its application in the evaluation of three species of Stephania. J Pharm Biomed Anal. 2018 Jul 15;156:284-296.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
709.7±60.0 °C at 760 mmHg

[ Molecular Formula ]:
C₃₇H₄₀N₂O₆

[ Molecular Weight ]:
608.723

[ Flash Point ]:
383.0±32.9 °C

[ Exact Mass ]:
608.288635

[ PSA ]:
72.86000

[ LogP ]:
3.78

[ Vapour Pressure ]:
0.0±2.3 mmHg at 25°C

[ Index of Refraction ]:
1.602

Related Compounds

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