(E)-Ligustilide
Names
[ CAS No. ]:
81944-08-3
[ Name ]:
(E)-Ligustilide
[Synonym ]:
E-ligustilide
3-But-(E)-ylidene-4,5-dihydro-3H-isobenzofuran-1-one
(E)-Ligustilide
Biological Activity
[Description]:
(E)-Ligustilide is isolated from Angelica sinensis and has nephroprotective effects[1]。
[Related Catalog]:
[In Vitro]
(E)-Ligustilide (50 μM; 24-72 hours) decreases HK-2 cell survival to 86%, to 67% and to 49% for 24, 48 or 72 hours incubation, respectively[1]. (E)-Ligustilide (50 μM; 48-72 hours) alone decreases the metabolic activity to 87±6% and 71±8% after 48 and 72 h incubation, respectively, as compared to the control condition in HK-2 cells[1]. Cell Viability Assay[1] Cell Line: HK-2 cell Concentration: 50 μM Incubation Time: 24 hours, 48 hours and 72 hours Result: Decreased cell survival as a dose-dependent manner.
[References]
Chemical & Physical Properties
[ Molecular Formula ]:
C12H14O2
[ Molecular Weight ]:
190.23800
[ Exact Mass ]:
190.09900
[ PSA ]:
26.30000
[ LogP ]:
2.87380
[ Storage condition ]:
-20°C