L-Aspartic acid-d3

Names

[ Name ]:
L-Aspartic acid-d3

[Synonym ]:
L-Asparagic Acid-d3
L-Aminosuccinic Acid-d3
L-aspartic-2,3,3-d3 acid
L-Aspartic Acid-d3
L-Asparaginic Acid-d3
L-(2,3,3-H)Aspartic acid
S)-2-Aminobutanedioic Acid-d3
L-Aspartic-2,3,3-d acid
L-Aspartic acid-2,3,3-d3
L-Deuterio-asparaginsaeure
MFCD00144564

Biological Activity

[Description]:

L-Aspartic acid-d3 is the deuterium labeled L-Aspartic acid. L-Aspartic acid is is an amino acid, shown to be a suitable prodrug for colon-specific drug deliverly.

[Related Catalog]:

Research Areas >> Cardiovascular Disease

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
264.1±30.0 °C at 760 mmHg

[ Melting Point ]:
>300ºC (dec.)(lit.)

[ Molecular Formula ]:
C₄H₄D₃NO₄

[ Molecular Weight ]:
136.121

[ Flash Point ]:
113.5±24.6 °C

[ Exact Mass ]:
136.056335

[ PSA ]:
100.62000

[ LogP ]:
-0.67

[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C

[ Index of Refraction ]:
1.531

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3