diSPhMC-Asn-Pro-Val-PABC-MMAE

Names

[ CAS No. ]:
2893871-68-4

[ Name ]:
diSPhMC-Asn-Pro-Val-PABC-MMAE

Biological Activity

[Description]:

diSPhMC-Asn-Pro-Val-PABC-MMAE (compound 9) is a potent ADC Linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker

[References]

[1]. Mohamed Amar IA, et al. Dual intra- and extracellular release of monomethyl auristatin E from a neutrophil elastase-sensitive antibody-drug conjugate. Eur J Med Chem. 2022 Feb 5;229:114063.  

Chemical & Physical Properties

[ Molecular Formula ]:
C83H115N11O16S2

[ Molecular Weight ]:
1587.00

Related Compounds