IDO1-IN-16

Names

[ CAS No. ]:
2677054-63-4

[ Name ]:
IDO1-IN-16

Biological Activity

[Description]:

IDO1-IN-16 (I-1) is an IDO1 inhibitor targeting holo-IDO1, with an IC50 of 127 nM[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Metabolic Enzyme/Protease >> Indoleamine 2,3-Dioxygenase (IDO)

[Target]

IDO1:127 nM (IC50)

[References]

[1]. Yunze Wu, et al. Discovery of novel IDO1 inhibitors targeting the protein's apo form through scaffold hopping from holo-IDO1 inhibitor. Bioorg Med Chem Lett. 2021 Nov 15;52:128373.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₅H₃₅BrFN₅O₂

[ Molecular Weight ]:
536.48

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.