Vasopressin V2 receptor antagonist 1

Names

[ CAS No. ]:
2648650-50-2

[ Name ]:
Vasopressin V2 receptor antagonist 1

Biological Activity

[Description]:

Vasopressin V2 receptor antagonist 1 (Compound 4g) is a vasopressin V2 receptor (V2R) antagonist with a Ki of 3.8 nM. Vasopressin V2 receptor antagonist 1 can be used for autosomal dominant polycystic kidney disease (ADPKD) research[1].

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> Vasopressin Receptor
Research Areas >> Metabolic Disease

[Target]

Ki: 3.8 nM (vasopressin V2 receptor)[1]


[References]

[1]. Haoran Zhang, et al. Long Residence Time at the Vasopressin V2 Receptor Translates into Superior Inhibitory Effects in Ex Vivo and In Vivo Models of Autosomal Dominant Polycystic Kidney Disease. J Med Chem. 2022 Apr 1.

Chemical & Physical Properties

[ Molecular Formula ]:
C33H37ClN4O4

[ Molecular Weight ]:
589.12

Related Compounds