BCN-PEG3-VC-PFP ester

Names

[ CAS No. ]:
2353409-45-5

[ Name ]:
BCN-PEG3-VC-PFP ester

Biological Activity

[Description]:

BCN-PEG3-VC-PFP ester is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker

[Target]

Cleavable


[In Vitro]

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

[References]

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

Chemical & Physical Properties

[ Molecular Formula ]:
C37H50F5N5O10

[ Molecular Weight ]:
819.81

Related Compounds