Boc-Leu-OH·H2O-13C

Names

[ CAS No. ]:
201740-80-9

[ Name ]:
Boc-Leu-OH·H2O-13C

[Synonym ]:
N-(tert-Butoxycarbonyl)-L-leucine-1-13C monohydrate
MFCD01075515
Boc-Leu-OH-1-13C monohydrate
L-Leucine-1-13C,N-t-Boc derivative monohydrate

Biological Activity

[Description]:

Boc-Leu-OH·H2O-13C is a 13C-labeled γ-Tocotrienol. γ-Tocotrienol is an active form of vitamin E[1].

[Related Catalog]:

Research Areas >> Inflammation/Immunology
Research Areas >> Metabolic Disease

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[75].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-225.

[2]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-225.

Chemical & Physical Properties

[ Melting Point ]:
85-87 ℃(lit.)

[ Molecular Formula ]:
C1013CH23NO5

[ Molecular Weight ]:
250.30

[ Exact Mass ]:
250.16100

[ PSA ]:
88.35000

[ LogP ]:
2.15050

Safety Information

[ RIDADR ]:
NONH for all modes of transport

Related Compounds