Lactalbumin B (50-53) Alpha [Lactorphin Alpha], bovine

Names

[ CAS No. ]:
198284-23-0

[ Name ]:
Lactalbumin B (50-53) Alpha [Lactorphin Alpha], bovine

[Synonym ]:
L-Phenylalanine,L-tyrosylglycyl-L-leucyl

Biological Activity

[Description]:

Lactalbumin B (50-53) Alpha [Lactorphin Alpha], bovine is a blood pressure lowering peptide containing 4 amino acids. Lactalbumin B (50-53) Alpha [Lactorphin Alpha], bovine is an angiotensin-converting Enzyme (ACE) inhibitor. Lactalbumin B (50-53) Alpha [Lactorphin Alpha], bovine can be used in research of high blood pressure[1].

[Related Catalog]:

Research Areas >> Cardiovascular Disease

Signaling Pathways >> Metabolic Enzyme/Protease >> Angiotensin-converting Enzyme (ACE)

[In Vivo]

Lactalbumin B (50-53) Alpha [Lactorphin Alpha], bovine (1-1000 μg/kg; s.c.) inhibits blood pressure in normotensive and spontaneously hypertensive rats[1]. Animal Model: Adult male SHR and WKY rats[1] Dosage: 1, 10, 100, and 1000 μg/kg Administration: Subcutaneous injection Result: Inhibited blood pressure in a dose-dependent manner.

[References]

[1]. Nurminen MN, et, al. α-Lactorphin lowers blood pressure measured by radiotelemetry in normotensive and spontaneously hypertensive rats. Life Sciences. 2000 Mar 10;66(16):1535-43.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₆H₃₄N₄O₆

[ Molecular Weight ]:
498.57100

[ Exact Mass ]:
498.24800

[ PSA ]:
181.32000

[ LogP ]:
3.94240

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.