Trimethylammonium chloride-d9

Names

[ Name ]:
Trimethylammonium chloride-d9

[Synonym ]:
1,1,1-trideuterio-N,N-bis(trideuteriomethyl)methanamine,hydrochloride

Biological Activity

[Description]:

Trimethylammonium chloride-d9 is the deuterium labeled Trimethylammonium chloride[1]. Trimethylammonium chloride is an endogenous metabolite.

[Related Catalog]:

Research Areas >> Metabolic Disease

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

Chemical & Physical Properties

[ Melting Point ]:
283-284ºC(lit.)

[ Molecular Formula ]:
C₃HClD₉N

[ Molecular Weight ]:
104.62700

[ Exact Mass ]:
104.10700

[ PSA ]:
3.24000

[ LogP ]:
0.97980

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26

[ RIDADR ]:
NONH for all modes of transport