7-chloro-5-(2-fluorophenyl)-3-hydroxy-1,3-dihydro-1,4-benzodiazepin-2-one
Names
[ CAS No. ]:
17617-60-6
[ Name ]:
7-chloro-5-(2-fluorophenyl)-3-hydroxy-1,3-dihydro-1,4-benzodiazepin-2-one
[Synonym ]:
Ro 7-5205
3-Hydroxy-N-desalkyl-2-oxoquazepam
OX 164F
Chemical & Physical Properties
[ Density]:
1.48g/cm3
[ Boiling Point ]:
507.1ºC at 760mmHg
[ Molecular Formula ]:
C15H10ClFN2O2
[ Molecular Weight ]:
304.70400
[ Flash Point ]:
260.5ºC
[ Exact Mass ]:
304.04100
[ PSA ]:
61.69000
[ LogP ]:
2.16060
[ Vapour Pressure ]:
4.18E-11mmHg at 25°C
[ Index of Refraction ]:
1.668
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- DF2370105
- CHEMICAL NAME :
- 2H-1,4-Benzodiazepin-2-one, 1,3-dihydro-7-chloro-5-(o-fluorophenyl)-3-hydroxy-
- CAS REGISTRY NUMBER :
- 17617-60-6
- BEILSTEIN REFERENCE NO. :
- 0759083
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C15-H10-Cl-F-N2-O2
- MOLECULAR WEIGHT :
- 304.72
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 774 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PHMGBN Pharmacology: International Journal of Experimental and Clinical Pharmacology. (S. Karger AG, Postfach CH-4009 Basel, Switzerland) V.1- 1968- Volume(issue)/page/year: 12,74,1974