Amino-PEG4-Val-Cit-PAB-MMAE

Names

[ CAS No. ]:
1492056-71-9

[ Name ]:
Amino-PEG4-Val-Cit-PAB-MMAE

Biological Activity

[Description]:

Amino-PEG4-Val-Cit-PAB-MMAE is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker

[Target]

Cleavable


[In Vitro]

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

[References]

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

Chemical & Physical Properties

[ Molecular Formula ]:
C69H115N11O17

[ Molecular Weight ]:
1370.71

[ Storage condition ]:
2-8°C

Related Compounds