(D-Trp6)-LHRH (free acid) trifluoroacetate salt

Names

[ CAS No. ]:
129418-54-8

[ Name ]:
(D-Trp6)-LHRH (free acid) trifluoroacetate salt

[Synonym ]:
(D-Trp6)-LHRH (free acid), Triptorelin (free acid)
(D-TRP6)-LHRH (FREE ACID)

Biological Activity

[Description]:

(D-Trp6)-LHRH free acid is a luteinizing hormone-releasing hormone (LHRH) agonist[1].

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> GNRH Receptor
Research Areas >> Cancer

[In Vitro]

(D-Trp6)-LHRH (10 μM; 24 h or 6 days) free acid 降低人上皮性卵巢癌细胞系 EFO-21 和 EFO-27 的增殖[1]。

[References]

[1]. Emons G, et al. High affinity binding and direct antiproliferative effects of LHRH analogues in human ovarian cancer cell lines. Cancer Res. 1993 Nov 15;53(22):5439-46.  

Chemical & Physical Properties

[ Molecular Formula ]:
C64H81N17O14

[ Molecular Weight ]:
1312.43000

[ Exact Mass ]:
1311.61000

[ PSA ]:
482.13000

[ LogP ]:
3.09900


Related Compounds

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